Say yes to a new day, new opportunities and new experiences.
In most colleges, students are required to take Core classes to strengthen basic skills, to get a better understanding of themselves and the world around them, and to broaden their horizons. Once a person graduates, he should make a point to continue trying new things.
There will always be people who will try to discourage others from stepping out of a comfort zone and exploring new avenues. However, a person should not let the fears of others hold him back.
Not every experience will be enjoyable, but there could be some pleasant surprises along the way.